Unexpected hydrazinolysis behaviour of 1-chloro-4-methyl-5H-pyridazino[4,5-b]indole and a convenient synthesis of new [1,2,4]-triazolo[4',3':1,6]pyridazino[4,5-b]indoles |
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Authors: | El-Kashef Hussein Farghaly Abdelrahman A H Haider Norbert Wobus Andrea |
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Institution: | Chemistry Department, Faculty of Science, Assiut University, 71516 Assiut, Egypt. |
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Abstract: | Reaction of the title compound with hydrazine in the presence of air gives the 1-unsubstituted parent system via oxidative dehydrazination of the 1-hydrazino intermediate. The latter can be obtained in high yield by carrying out the hydrazinolysis step under inert gas, and it is smoothly converted into 1,2,4]-triazolo4',3':1,6]pyridazino4,5- b]indoles. |
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