Separation of nitroimidazoles by reversed-phase high-pressure liquid chromatography |
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| Authors: | Sithole B B Guy R D |
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| Institution: | Trace Analysis Research Centre, Chemistry Department, Dalhousie University, Halifax, Nova Scotia, Canada. |
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| Abstract: | A mixture of eight N-substituted and unsubstituted nitroimidazoles has been separated by high-pressure liquid chromatography with 5% ethanol as the eluent. Compounds with the same capacity ratios were selectively detected electrochemically by differential pulse polarography with a hanging mercury drop electrode. The HMDE detector had higher detection limits than the photometric detector set at 315 nm. |
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