Determination of levamisole hydrochloride with HgI(2-)4 by a turbidimetric method and flow-injection analysis

This paper is concerned with the use of ion-association compounds in the analysis of pharmaceutical samples by FIA. The usual extraction into an organic phase is avoided by using turbidimetric detection. Determination of levamisole with HgI(2-)(4) has been developed as a practical example: the experimental variables were optimized by the modified simplex method. The calibration graph is linear over the levamisole concentration range 7-32 microg ml . The reproducibility (rsd) and injection sample rate are 0.9% and 80/hr, respectively.