Comparing dendritic with linear esterase peptides by screening SPOT arrays for catalysis |
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Authors: | Biswas Rasomoy Maillard Noélie Kofoed Jacob Reymond Jean-Louis |
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Institution: | Department of Chemistry and Biochemistry, University of Berne, Freiestrasse 3, CH-3012 Berne, Switzerland. |
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Abstract: | Fluorescence screening of a 96-membered SPOT library of histidine containing dendritic and linear peptides revealed the remarkable esterolytic activity of short histidine oligomers that show catalytic proficiencies within one order of magnitude of histidine-containing esterase peptide dendrimers. |
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