A convenient synthesis of dihydrocoumarins from phenols and cinnamic acid derivatives |
| |
| Authors: | Shinya Aoki |
| |
| Affiliation: | Department of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, Honjo-machi, Saga 840-8502, Japan |
| |
| Abstract: | A facile procedure for synthesis of dihydrocoumarin derivatives was described. Although the yield of the products in the reaction of phenols with acrylates in trifluoroacetic acid in the presence of Pd(OAc)2 giving coumarins was found to be very low, dihydrocoumarin derivatives were obtained in good to high yields in the absence of Pd(OAc)2 when ethyl cinnamates bearing electron-donating groups were employed in this reaction. |
| |
| Keywords: | Dihydrocoumarins Phenols Cinnamic acid derivatives Trifluoroacetic acid |
| 本文献已被 ScienceDirect 等数据库收录！ |
