Iridium-catalyzed enantioselective cycloisomerization of nitrogen-bridged 1,6-enynes to 3-azabicylo[4.1.0]heptenes |
| |
| Authors: | Takanori Shibata Yuka Kobayashi Natsuko Toshida |
| |
| Affiliation: | a Department of Chemistry, School of Science and Engineering, Waseda University, Shinjuku, Tokyo, 169-8555, Japan
b Department of Chemistry, Faculty of Science, Okayama University, Tsushima, Okayama, 700-8530, Japan |
| |
| Abstract: | A cationic iridium complex catalyzes a cycloisomerization of nitrogen-bridged 1,6-enynes to give 3-azabicyclo[4.1.0]heptenes in good to high yield. When an iridium-chiral diphosphine complex is used, the reaction proceeds enantiomerically to give chiral cyclopropanes fused by a six-membered ring system. |
| |
| Keywords: | Iridium Enynes Cycloisomerization Enantioselective Cyclopropanes |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
