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Regioselective reactivity of some 5,7-dimethoxyindoles
Authors:Glenn C. Condie
Affiliation:School of Chemistry, University of New South Wales, UNSW Sydney NSW 2052, Australia
Abstract:The reactivity of some 5,7-dimethoxyindoles with respect to electrophiles has been investigated. The favoured sites for reaction are C3 and C4 and regioselectivity can be controlled by the judicious arrangement of electron-withdrawing substituents. Results of formylation, acylation, the Mannich reaction, bromination and nitration are described.
Keywords:Indoles   Formylation   Acylation   Regioselectivity
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