Regioselective reactivity of some 5,7-dimethoxyindoles |
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Authors: | Glenn C. Condie |
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Affiliation: | School of Chemistry, University of New South Wales, UNSW Sydney NSW 2052, Australia |
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Abstract: | The reactivity of some 5,7-dimethoxyindoles with respect to electrophiles has been investigated. The favoured sites for reaction are C3 and C4 and regioselectivity can be controlled by the judicious arrangement of electron-withdrawing substituents. Results of formylation, acylation, the Mannich reaction, bromination and nitration are described. |
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Keywords: | Indoles Formylation Acylation Regioselectivity |
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