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Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii
Authors:Nagy Morsy  Toshihiro Houdai  Seiji Adachi  Takashi Iwashita
Affiliation:a Department of Chemistry, Graduate School of Science, Osaka University, Machikaneyama, Toyonaka, Osaka 560-0043, Japan
b Suntory Institute for Bioorganic Research, 1-1-1 Wakayamadai, Shimamotocho, Osaka 618-8503, Japan
Abstract:A new member of amphidinols (AM7) possessing a polyene-polyhydroxyl structure with the shortest carbon backbone and sulfate ester was isolated from the cultured dinoflagellate, Amphidinium klebsii. AM7 showed hemolytic and antifungal activities. The structure was elucidated on the basis of 2D NMR data in combination with CID MS/MS experiments.
Keywords:Amphidinol   Amphidinium   AM7   AM3   CID MS/MS
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