| 抗癌新药安吖啶的近红外拉曼光谱及近红外表面增强拉曼光谱的研究 |
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| 引用本文： | 田惠军. 抗癌新药安吖啶的近红外拉曼光谱及近红外表面增强拉曼光谱的研究[J]. 光谱学与光谱分析, 1998, 18(3): 289-292 |
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| 作者姓名： | 田惠军 |
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| 作者单位： | 军事医学科学院国家生物医学分析中心 |
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| 摘 要： | 采用近红外表面增强拉曼光谱技术对抗癌新药安吖啶的结构进行了研究。
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| 关 键 词： | 安吖啶 近红外拉曼光谱 结构 SERS 分析 |
Study on the NIR-Raman spectra and NIR-SERS spectra of amsacrine] |
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| H Tian,B Liu,Z Song,S Shen,J Han,Y Fang. Study on the NIR-Raman spectra and NIR-SERS spectra of amsacrine][J]. Spectroscopy and Spectral Analysis, 1998, 18(3): 289-292 |
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| Authors: | H Tian B Liu Z Song S Shen J Han Y Fang |
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| Affiliation: | National Center of Biomedical Analysis, Academy of Military Medical Sciences, 100850 Beijing. |
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| Abstract: | The near infrared surface-enhanced Raman spectra (NIR-SERS) of amsacrine,an anticancer agent, on silver collids were recored with high quality. The NIR-SERS enhancement factor is up to 10(4) magnitude. In comparison with the near infrared Raman (NIR-Raman) spectra of solid amsacrine, more information of vibrational structures of amsacrine molecules at low concentration and almost in its practical application envi ronment, can be given by the NIR-SERS. The enhancement mechanism is associated with the adsorption of acridyl ring and sulfonyl on silver surface. |
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