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Frustrated Lewis Pair Chemistry: Development and Perspectives |
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| Authors: | Prof Dr Douglas W Stephan Prof Dr Gerhard Erker |
| Institution: | 1. Department of Chemistry, University of Toronto, 80 St. George St, Toronto, Ontario M5S3H6 (Canada);2. Organisch Chemisches Institut, Westf?lische Wilhelms‐Universit?t, Corrensstr. 40, 48149 Münster (Germany) |
| Abstract: | Frustrated Lewis pairs (FLPs) are combinations of Lewis acids and Lewis bases in solution that are deterred from strong adduct formation by steric and/or electronic factors. This opens pathways to novel cooperative reactions with added substrates. Small‐molecule binding and activation by FLPs has led to the discovery of a variety of new reactions through unprecedented pathways. Hydrogen activation and subsequent manipulation in metal‐free catalytic hydrogenations is a frequently observed feature of many FLPs. The current state of this young but rapidly expanding field is outlined in this Review and the future directions for its broadening sphere of impact are considered. |
| Keywords: | cooperative reactions frustrated Lewis pairs metal‐free hydrogenation small‐molecule activation |