Acquired Superoxide‐Scavenging Ability of Ceria Nanoparticles |
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| Authors: | Yuanyuan Li Dr. Xiao He Prof. Jun‐Jie Yin Dr. Yuhui Ma Dr. Peng Zhang Dr. Jingyuan Li Dr. Yayun Ding Dr. Jing Zhang Prof. Yuliang Zhao Prof. Zhifang Chai Prof. Zhiyong Zhang |
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| Affiliation: | 1. Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Key Laboratory of Nuclear Radiation and Nuclear Energy Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China);2. Division of Analytical Chemistry, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD 20740 (USA);3. Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China) |
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| Abstract: | Ceria nanoparticles (nanoceria) are well known as a superoxide scavenger. However, inherent superoxide‐scavenging ability has only been found in the nanoceria with sizes of less than 5 nm and with very limited shape diversity. Reported herein is a strategy to significantly improve the superoxide‐scavenging activity of nanoceria sized at greater than 5 nm. The nanoceria with sizes of greater than 5 nm, with different shapes, and with a negligible Ce3+/Ce4+ ratio can acquire remarkable superoxide‐scavenging abilities through electron transfer. This method will make it possible to develop nanoceria‐based superoxide‐scavengers with long‐acting activity and tailorable characteristics. |
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| Keywords: | cerium electron transfer nanoparticles oxides surface chemistry |
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