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Discovery,Structure Elucidation,and Biological Characterization of Nannocystin A,a Macrocyclic Myxobacterial Metabolite with Potent Antiproliferative Properties |
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| Authors: | Dr Holger Hoffmann Priv‐Doz Dr Herbert Kogler Dipl‐Ing Winfried Heyse Dr Hans Matter Dr Michael Caspers Prof Dr Dietmar Schummer Dr Christine Klemke‐Jahn Dr Armin Bauer Dr Geraldine Penarier Dr Laurent Debussche Prof Dr Mark Brönstrup |
| Institution: | 1. Sanofi R&D, Industriepark Hoechst, 65926 Frankfurt (Germany);2. Current address: Institut für Analytische Chemie, Universit?t Bremen, Leobener Str. NW IIC 28359 Bremen (Germany);3. Current address: TH Mittelhessen, Wiesenstra?e 14, 35390 Gie?en (Germany);4. Sanofi R&D, 13 Quai Jules Guesde, Vitry sur Seine 94403 (France);5. Current address: Department of Chemical Biology, Helmholtz Zentrum für Infektionsforschung, Inhoffenstr 7, 38124 Braunschweig (Germany) |
| Abstract: | |
| Keywords: | apoptosis antiproliferative agents drug discovery natural products structure elucidation |