Synthesis and in vitro antitumor activity of some triarylantimony di(N-phenylglycinates) |
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| Authors: | Lin Yu Yong-Qiang Ma Guo-Cang Wang Jin-Shan Li |
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| Affiliation: | State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China |
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| Abstract: | Triarylantimony(V) di(N-phenylglycinates) (PhNHCH2COO)2SbAr3 (Ar = Ph, p-CH3C6H4, p-ClC6H4, and p-FC6H4) have been synthesized and characterized by elemental analysis, IR, 1H NMR, and mass spectra. The crystal structure of (PhNHCH2COO)2Sb(C6H4F-p)3 has been determined by X-ray diffraction. The in vitro antitumor activities of these compounds against three cancer cell lines are reported. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 15:32–36, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10208 |
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