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Engineered Green Fluorescence Proteins for Proteomics and Biomolecular Electronic Applications
Authors:Ranieri Bizzarri  Vittorio Pellegrini  Caterina Arcangeli  Aldo Ferrari  Riccardo Nifosì  Pasqualantonio Pingue  Valentina Tozzini  Mauro Giacca  Fabio Beltram
Affiliation:1. NEST-INFM, Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126 Pisa, Italy;2. Molecular Medicine Laboratory, International Center for Genetic Engineering and Biotechnology, Padriciano 99, I-34012 Trieste, Italy
Abstract:The discovery of the photochromic characteristics of engineered green fluorescent proteins (GFPs) allows new proteomics and biomolecular electronic applications. In particular, photoreversibility among two distinct optical states can lead to the realization of a bio-optical high density storage memory. Here we review our recent work on an optically bistable GFP and we report the recent developments of self-assembly methods for spatial immobilization of proteins into well-definite 2D patterns.
Keywords:fluorescence  lithography  molecular dynamics  nanotechnology  protein photophysics  self-assembly
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