The Photochemical Behavior of Nalidixic Acid

The influence of intermolecular proton transfer on the spectral properties of nalidixic acid (nlqH) in the ground and excited electronic states was studied. A scheme of possible protolytic reactions that occurred in this compound under the action of pH and UV radiation in aqueous medium was constructed. The total energies of model nlqH molecules in the monomeric and dimeric states were calculated quantum-chemically. Proton transfer was found to substantially influence the radiation capacity of nlqH related to the protonation and dimerization of molecules. Original Russian Text ? A.V. Polishchuk, M.V. Kazachek, E.T. Karaseva, V.E. Karasev, 2008, published in Zhurnal Fizicheskoi Khimii, 2008, Vol. 82, No. 4, pp. 754–758.