Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter |
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Authors: | Pankaj Chauhan Swapandeep Singh Chimni |
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Institution: | U.G.C. Sponsored Centre for Advance Studies in Chemistry, Department of Chemistry, Guru Nanak Dev University, Amritsar 143005, India |
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Abstract: | 3-Amino-2-oxindoles bearing tetra-substituted stereocenter are very important constituents of many bioactive and pharmaceutical agents. In the last few years, asymmetric organocatalysis emerged as an excellent approach for the synthesis of optically active 3-substituted-3-amino-2-oxindoles. This review describes the various organocatalytic enantioselective strategies for the synthesis of 3-substituted 3-amino-2-oxindole frameworks. |
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