Synthesis and evaluation of the catalytic properties of semicarbazides derived from N-triphenylmethyl-aziridine-2-carbohydrazides |
| |
Authors: | Stanisław Leśniak Adam M. Pieczonka Szymon Jarzyński Katarzyna Justyna Michał Rachwalski |
| |
Affiliation: | University of ?ód?, Department of Organic and Applied Chemistry, Tamka 12, PL-91-403 ?ód?, Poland |
| |
Abstract: | A straightforward synthesis of a series of new catalysts derived from N-triphenylmethyl-aziridine-2-carbohydrazides is described. The new compounds have been tested for the enantioselective addition of diethyl- and phenylethynylzinc to aryl and alkyl aldehydes, which afforded the corresponding chiral alcohols in high chemical yields (up to 92%) and with excellent ee’s of approximately 90%. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |