| 毛细管电泳在手性化合物分离中的应用进展 |
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| 引用本文： | 潘聪洁,王伟峰,陈兴国.毛细管电泳在手性化合物分离中的应用进展[J].色谱,2016,34(1):16-20. |
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| 作者姓名： | 潘聪洁 王伟峰 陈兴国 |
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| 作者单位： | 1. 兰州大学化学化工学院, 甘肃 兰州 730000;
2. 功能有机分子化学国家重点实验室, 甘肃 兰州 730000;
3. 甘肃省有色金属化学与资源利用重点实验室, 甘肃 兰州 730000 |
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| 基金项目： | 国家自然科学基金项目(21375053). |
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| 摘 要： | 由于手性化合物尤其是手性药物的两个对映体具有不同的化学性质和生理活性,对手性化合物进行分离在医药、生物、食品和环境等领域都具有十分重要的意义。毛细管电泳由于其独特的优势已广泛应用于手性物质的分离。本文对2013~2015年毛细管电泳用于手性分离的最新进展进行了综述,并对其发展前景进行了展望。
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| 关 键 词： | 进展 毛细管电泳 手性分离 综述 |
| 收稿时间： | 2015-09-02 |
Recent developments of chiral separation by capillary electrophoresis |
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| PAN Congjie,WANG Weifeng,CHEN Xingguo.Recent developments of chiral separation by capillary electrophoresis[J].Chinese Journal of Chromatography,2016,34(1):16-20. |
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| Authors: | PAN Congjie WANG Weifeng CHEN Xingguo |
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| Institution: | 1. College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China;
2. State Key Laboratory of Applied Organic Chemistry, Lanzhou 730000, China;
3. Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou 730000, China |
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| Abstract: | As the two enantiomers of chiral compounds have different chemical and physiologic properties, the enantioseparation of chiral compounds is of great significance in the fields such as medicine, biology, food and environment. Hence, the enantioseparation of different types of chiral compounds has become one of the hottest research topics in recent years. Capillary electrophoresis, owing to its unique advantages, has a wide application in the enantioseparation field recently. In this review, the latest research progresses in capillary electrophoresis enantioseparation are summarized from 2013 to 2015, and the future developments in this field is also prospected. |
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| Keywords: | capillary electrophoresis (CE) enantioseparation progress review |
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