Eco-friendly synthesis of 2-substituted benzothiazoles catalyzed by silica sulfuric acid |
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| Authors: | Guo Feng Chen Li Yan Zhang Hui Ming Jia Bao Hua Chen Ji Tai Li Shu Xiang Wang Guo Yi Bai |
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| Institution: | 1. Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Wusi East Road No. 180, Baoding, 071002, People’s Republic of China
2. College of Pharmaceutical Sciences, Hebei University, Baoding, 071002, People’s Republic of China
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| Abstract: | 2-Substituted benzothiazoles have been synthesized via one-pot reaction from aromatic aldehydes and o-aminothiophenol catalyzed by silica sulfuric acid in absolute methanol at room temperature. The remarkable advantages offered by this method are an environmentally friendly and reusable catalyst, a simple procedure, mild conditions, short reaction times, and good to excellent yields of products. |
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