A synthesis of RGD model cyclic peptide by palladium-catalyzed carbonylative macrolactamization |
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| Authors: | Doi Takayuki Kamioka Seiji Shimazu Sayaka Takahashi Takashi |
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| Institution: | Department of Applied Chemistry, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro, Tokyo 152-8552, Japan. |
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| Abstract: | Cyclic peptidic RGD models were efficiently synthesized by Pd(P(t-Bu)3)2-catalyzed carbonylative macrolactamization in the presence of 4 A molecular sieves under 10 atm of carbon monoxide. |
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