New methods and reagents in organic synthesis. 62 trimethylsilyldiazomethane: A convenient reagent for the preparation of acylsilanes |
| |
| Affiliation: | 1. Phosphorus Laboratory, Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India;2. Department of Chemistry, Tulane University, New Orlens, Louisiana, 70118, United States;1. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic;2. Department of Organic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, CZ-12843 Prague 2, Czech Republic |
| |
| Abstract: | The lithium salt of trimethylsilyldiazomethane smoothly reacts with alkyl halides to give α-trimethylsilyldiazoalkanes which are easily oxidized with m-chloroperbenzoic acid (m-CPBA), giving the corresponding acylsilanes (α-ketosilanes) in good yields. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
