Regioselective titanium mediated reductive opening of 2,3-epoxy alcohols |
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| Affiliation: | 1. School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Rd, Melbourne, VIC 3004, Australia;2. Department of Physiotherapy, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia;3. Health Data Research UK, Swansea University Medical School, Swansea University, United Kingdom;4. Baker Heart and Diabetes Institute, Melbourne, Australia;5. Alfred Emergency and Trauma Centre, Melbourne, Australia |
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| Abstract: | Lithium borohydride reduction of 2,3-epoxy alcohols was shown to yield 1,2-diols in high regioselectivity with the aid of titanium tetraisopropoxide in benzene solution. |
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