A novel approach to carbocyclic analogues of nucleosides |
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| Affiliation: | 1. Instituto de Química del Sur (INQUISUR), Departamento de Química, Universidad Nacional del Sur, Avenida Alem 1253, 8000 Bahía Blanca, Argentina;2. CONICET, Argentina;3. Laboratorio de Instrumental de Uso Compartido (LIUC), INQUISUR (UNS-CONICET), Argentina |
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| Abstract: | (±)-1-[(1α,3α,4α)-3-Hydroxy-4-hydroxymethlcyclopentyl]- (1H,3H-pyrimidin-2,4-dione (6) was synthesized starting from endo-5-norbornen-2-yl acetate via the urea derivative 5 in 32% overall yield. |
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