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Phase managed organic synthesis 2. A new polymer assisted synthesis of acid anhydrides.
Affiliation:1. Max Planck Institute for Chemical Energy Conversion, Stiftstrasse 34, 45470 Mülheim an der Ruhr, Germany;2. Department of Bio- and Chemical Engineering, Laboratory of Industrial Chemistry, Technical University of Dortmund, Emil-Figge-Straße 66, 44227 Dortmund, Germany;1. Instituto de Polímeros e Compósitos/I3N, Universidade do Minho, 4800-058 Guimarães, Portugal;2. Centro de Química, Universidade do Minho, 4710-057 Braga, Portugal;3. Departamento de Informática, Centro ALGORITMI, Universidade do Minho, 4710-057 Braga, Portugal;4. Instituto Nacional del Carbón, INCAR-CSIC, Apartado 73, 33080 Oviedo, Spain;1. Department of Chemistry, Ben-Gurion University, Beer Sheva 84105, Israel;2. Department of Chemistry, University of Douala, PO Box 2701, Douala, Cameroon;3. Department of Biotechnology Engineering, Ben-Gurion University, Beer Sheva 84105, Israel;4. Department of Clinical Biochemistry, Ben-Gurion University, Beer Sheva 84105, Israel;1. Department of Chemical and Biological Engineering, Drexel University, Philadelphia, PA, United States;2. Department of Chemistry, University of Pennsylvania, Philadelphia, PA, United States;1. Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary;2. MTA-SZTE Stereochemistry Research Group, Dóm tér 8, H-6720 Szeged, Hungary
Abstract:A solid-phase copolymer of 4-vinylpyridine is shown to be a highly effective reagent/ catalyst for the synthesis of acid anhydrides from mixtures containing equimolar quantities of carboxylic acids and acid chlorides. The process may be carried out in batch or column mode.
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