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Total syntheses of rothin-A and rothin-B
Affiliation:1. Drug Research and Development Center, Daegu Catholic University, Gyeongsan, 38430, Republic of Korea;2. Phutho College of Pharmacy, Viettri City, Phutho Province, 290000, Viet Nam;3. School of Chemical and Material Engineering, Jiangnan University, Wuxi, 214122, China;4. College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea;5. School of Chemistry and Biochemistry, Yeungnam University, Gyeongsan, 38541, Republic of Korea;6. Department of Food Science & Nutrition, Pukyong National University, Busan, 48513, Republic of Korea;1. Department of Traditional Chinese Orthopedics, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China;2. Department of Emergency Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China;3. Department of Rheumatology and Immunology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China;1. Department of Chemistry, Panjab University and Centre of Advanced Studies in Chemistry, Chandigarh 160014, U. T., India;2. Department of Chemical Sciences, Indian Institute of Science Education and Research Mohali, Sector 81, S.A.S. Nagar 140306, Punjab, India
Abstract:The eudesmanolides rothin-A 1 and rothin-B 2 have been synthesized from (-)-artemisin in 7 and 9 steps, respectively.
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