A new synthetic approach to the benzazole ring system. Synthesis and electrocyclic ring closure of dialkenyl and alkenyl-aryl substituted pyrroles,imidazoles and oxazoles |
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| Affiliation: | 1. School of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar 752050, India;2. Institut für Anorganische Chemie, RWTH Aachen University, 52074 Aachen, Germany;1. School of Pharmacy, University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing 100049, China;2. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China;1. Department of Chemistry, QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal;2. Department of Chemistry, CICECO, University of Aveiro, 3810-193 Aveiro, Portugal;1. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, PR China;2. Department of Medicinal Chemistry, Beijing Key Laboratory of Active Substances Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, PR China;1. Organic Chemistry Group, QOPNA, Department of Chemistry, University of Aveiro, 3810-193, Aveiro, Portugal;2. Mass Spectrometry Centre, QOPNA, Department of Chemistry, University of Aveiro, 3810-193, Aveiro, Portugal;3. UCIBIO, REQUIMTE, Department of Chemistry, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal |
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| Abstract: | An efficient synthesis is described of the substituted azoles referred to in the title, which are precursors of an equally successful new synthetic approach to indoles, benzimidazoles and benzoxazoles. |
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