Total synthesis of optically active integerrimine,a twelve-membered dilactonic pyrrolizidine alkaloid of retronecine type. I. Enantioselective synthesis of the protected (+)-integerrinecic acid |
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| Affiliation: | 1. Institute of Food Safety and Environment Monitoring, Fuzhou University, Fuzhou, 350108, China;2. Institute of Chemical Safety, Fujian University of Technology, Fuzhou 350118, China;3. College of Materials Science and Engineering, Fuzhou University, Fuzhou, 350108, China |
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| Abstract: | For the total synthesis of optically active integerrimine, the twelve-membered dilactonic pyrrolizidine alkaloid, the necic acid component (+)-integerrinecic acid has been enantioselectively synthesized in the protected form. |
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