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Pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxides. Sulfur dioxide analogs of pteridines
Authors:Pilar Goya  Juan Antonio Paez  Wolfgang Pfleiderer
Institution:1. Instituto de Química Médica (C.S.I.C.), Juan de la Cierva, 3, Madrid-6, Spain;2. Fakultät für Chemie, Universität Konstanz, D-7750 Konstanz, West Germany
Abstract:Several pyrazino2,3-c]1,2,6]thiadiazine 2,2-dioxide derivatives have been synthesized for the first time by condensation of suitable 4,5-diamino-1,2,6-thiadiazine 1,1-dioxides and symmetrical 1,2-dicarbonyl compounds. Structures of these compounds have been characterized by their elementary analyses, 1H-nmr and uv spectra as well as their pKa values. The most striking differences between this series and the corresponding pteridines are discussed.
Keywords:
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