Reduction of the benzoyl group in substituted 5-benzoyl-4,5-dihydro-1,2,4-oxadiazoles |
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| Authors: | Benito Alcaide Gerardo Escobar Rafael Pérez-Ossorio Joaquin Plumet |
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| Institution: | Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Complutense, Ciudad Universitaria, Madrid-3, Spain |
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| Abstract: | The carbonyl group of substituted 5-benzoyl-4,5-dihydro-1,2,4-oxadiazoles can be reduced by lithium aluminium hydride at low temperature without ring opening. Mixtures of the two related diastereoisomeric benzylalcohols are obtained. Configurations were assigned by 1H-nmr. |
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