The effect of ionising radiation on poly(methyl methacrylate) used in intraocular lenses |
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Authors: | CM Pratt S Barton E McGonigle M Kishi PJS Foot |
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Institution: | Materials Research Group, School of Chemical and Pharmaceutical Sciences, Kingston University, Penrhyn Road, Kingston upon Thames, Surrey KT1 2EE, UK |
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Abstract: | Gamma radiation is increasingly being used to sterilise intraocular lenses (IOLs) made from poly(methyl methacrylate) (PMMA). In this study, samples of PMMA used in the fabrication of IOLs were exposed to irradiation doses typically used for their sterilisation. The effect of this treatment on the polymer was analysed by size-exclusion chromatography (SEC), UV-visible and infrared spectroscopy and scanning electron microscopy (SEM). The PMMA was found to have undergone chain scission, decarboxylation and colour change following the irradiation. |
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Keywords: | PMMA Intraocular Sterilisation Irradiation SEC FT-IR |
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