Synthetic studies toward lapidilectine-type Kopsia alkaloids |
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| Authors: | Schultz Erica E Pujanauski Brian G Sarpong Richmond |
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| Affiliation: | Department of Chemistry, University of California, Berkeley, California 94720, USA. |
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| Abstract: | A rapid synthesis of the tetracyclic core of Kopsia indole alkaloids related to lapidilectine B, grandilodine C, and tenuisine A is reported. Key to the success of this route was an efficient and scalable Ugi four-component coupling to install all the necessary carbons found in the natural products. |
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