| 固相萃取-硅烷化-气质联用分析尿中莠去津及其去烃基代谢物 |
| |
| 引用本文： | 王国强,朱昱,齐宝坤,谭家镒.固相萃取-硅烷化-气质联用分析尿中莠去津及其去烃基代谢物[J].分析化学,2009,37(3). |
| |
| 作者姓名： | 王国强 朱昱 齐宝坤 谭家镒 |
| |
| 作者单位： | 中国刑事警察学院法医系,沈阳,110035 |
| |
| 摘 要： | 建立了固相萃取-硅烷化-气质联用分析尿中除草剂莠去津(ATRZ)及其代谢物去异丙基莠去津(DIA)、去乙基莠去津(DEA)和去乙基去异丙基莠去津(DDA)的方法.尿样加入内标,碱化后用GDX501大孔树脂进行固相萃取,萃取物进行TMS衍生化,选择离子监测气质联用法分析.尿中ATRZ、DIA、DEA和DDA的提取率分别为85.3%、78.6%、80.2%和71.7%; 检出限分别为0.9、0.9、1.5和1.2 μg/L;在5～500 μg/L浓度范围内工作曲线的线性关系良好.方法可用于莠去津中毒者和职业接触者尿样的分析.
|
| 关 键 词： | 除草剂 莠去津 尿 气质联用法 硅烷基衍生化 固相萃取法 |
Solid Phase Extraction-Silyl Derivation-Gas Chromatography-Mass Spectrometry for the Analysis of Atrazine and Its N-Desalkalated Metabolites in Urine |
| |
| WANG Guo-Qiang,ZHU Yu,QI Bao-Kun,TAN Jia-Yi.Solid Phase Extraction-Silyl Derivation-Gas Chromatography-Mass Spectrometry for the Analysis of Atrazine and Its N-Desalkalated Metabolites in Urine[J].Chinese Journal of Analytical Chemistry,2009,37(3). |
| |
| Authors: | WANG Guo-Qiang ZHU Yu QI Bao-Kun TAN Jia-Yi |
| |
| Institution: | Legal Medicine Department of Criminal Police Colege of China;Shengyang 110035 |
| |
| Abstract: | A solid phase extraction-trimethylsilyl(TMS) derivation-gas chromatography/mass spectrometric method to detect and quantitate atrazine and its metabolites deisopropylatrazine(DIA),deethylatrazine(DEA) and didealkyl atrazine(DDA)]in urine was developed.The urine samples were basified,and extracted by solid phase extraction technique using GDX501 porous resin.The resulting extracts were TMS derivatized,and then analysed by gas chromatography-mass spectrometry in the selected ion monitoring mode.The extractio... |
| |
| Keywords: | Atrazine herbicide urine solid phase extraction trimethylsilyl derivatization gas chromato-graphy-mass spectrometry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
