Electrometric Studies on the Ternary Complexes of M(II) With Chlorpromazine and Some Amino Acids |
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Authors: | Mahmoud Khodari |
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Affiliation: | (1) Chemistry Department, Faculty of Science, South Valley University Qena, Egypt, EG |
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Abstract: | The stability constants for the binary M(II)- chlorpromazine hydrochloride (CPZ) and the ternary complexes M(II)-chlorpromazine-amino acid, have been studied using pH-measurements. The amino acids (aa) are: glycine, glutamic acid, histidine and the metal ions are: Cu(II), Zn(II), Co(II), Ni(II) and UO2(II). All experiments were carried out in the presence of 0.1 mol dm−3 KNO3. The resulting stability constants of the binary and the ternary complexes were compared. It was observed that the stability of the ternary complexes-except for glutamic acid – are lower than of the binary ones. Received October 22, 1998. Revision March 14, 1999. |
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Keywords: | . pH-measurements chlorpromazine hydrochloride amino acids ternary complexes. |
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