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Microwave promoted one-pot synthesis of 3-(2'-amino-3'-cyano-4'-arylpyrid-6'-yl) coumarins
Authors:Jian Feng Zhou  Gui Xia Gong  Feng Xia Zhu  San Jun Zhi
Abstract:A facile procedure for the synthesis of 3-(2'-amino-3'-cyano-4'-arylpyrid-6'-yl) coumarins are being reported starting from 3-acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carded out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR,1H NMR,and mass spectral data.
Keywords:3-(2'-Amino-3'-cyano-4'-arylpyrid-6'-yl) coumarin  Aromatic aldehyde  3-Acetylcoumarin  Microwave irradiation
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