Diagnostic imaging by energetic radioactive particle beams: applications in Bragg Peak cancer therapy |
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Authors: | Chatterjee A Takada E Torikoshi M Kanazawa M |
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Institution: | Lawrence Berkeley National Laboratory, University of California, Berkeley 94720, USA. |
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Abstract: | Researchers explore the use of Bragg Ionization Peak in radiotherapy for tumors. Considerations for the production of a high quality radioactive beam include secondary beam production efficiency, primary beam survival, and multiple scattering. A Positron Emitting Beam Analyzing camera was developed and tested at BEVALAC using a neon-19 beam stopping point. Results indicate that in homogeneous brain tissues, CT measurements and radioactive beam measurements are between 1-2 mm; there can be substantial difference between CT measurements and radioactive beam estimates if the beam stopping point crosses the fossae; random coincidences due to detector activation also appear as diffused images in the image plane of the beam stopping point; and further enhancements are necessary to make reliable measurements in the human trunk and complex brain regions. |
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