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| 红外光谱法对双黄连粉针剂的定性定量分析 | |
| 引用本文： | 阎姝,徐茂玲,图雅,李惠芬,孙素琴.红外光谱法对双黄连粉针剂的定性定量分析[J].光谱学与光谱分析,2009,29(6):1558-1561. |
| 作者姓名： | 阎姝 徐茂玲 图雅 李惠芬 孙素琴 |
| 作者单位： | 1. 天津中医药大学，天津 300193 2. 生命有机磷化学及化学生物学教育部重点实验室, 清华大学化学系，北京 100084 3. 天津医科大学，天津 300070 |
| 基金项目： | 国家自然科学基金地区科学基金 |
| 摘 要： | 通过分析双黄连粉针剂的红外光谱并与对照品进行比较，初步指认了粉针剂中各类成分的吸收峰，为定性质量分析提供了依据。建立了基于中红外光谱的黄芩苷与绿原酸含量校正模型。模型的R2值均在0.99以上，平均预测相对误差也低于4%，具有良好的拟合及预测能力。本研究结果说明，使用红外光谱法对双黄连粉针剂进行在线定性定量分析，方便快速，切实可行。 |
| 关 键 词： | 双黄连粉针剂 傅里叶变换红外光谱法 定性定量分析 |
| 收稿时间： | 2008/8/10 |
Qualitative and Quantitative Analysis of Shuanghuanglian Fenzhenji by FTIR |
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| YAN Shu,XU Mao-ling,TU Ya,LI Hui-fen,SUN Su-qin.Qualitative and Quantitative Analysis of Shuanghuanglian Fenzhenji by FTIR[J].Spectroscopy and Spectral Analysis,2009,29(6):1558-1561. | |
| Authors: | YAN Shu XU Mao-ling TU Ya LI Hui-fen SUN Su-qin |
| Institution: | 1. Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China2. Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China3. Tianjin Medical University，Tianjin 300070, China |
| Abstract: | Qualitative and quantitative analysis of Shuanghuanglian fenzhenji was studied in the present paper by FTIR.The fingerprint characteristics of main components in the injections were assigned and can be used as the criterion in the qualitative quality control.Calibration models by PLS algorithm were built to get the quantitative information of baicalin and chlorogenic acid in the injection samples.The R2 of calibration models are both above 0.99 and the average relative deviations between predicted and actua... |
| Keywords: | Shuanghuanglian fenzhenji FTIR Qualitative and quantitative analysis |
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