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Highly enantioselective [3+2] annulation of Morita-Baylis-Hillman adducts mediated by L-threonine-derived phosphines: synthesis of 3-spirocyclopentene-2-oxindoles having two contiguous quaternary centers
Authors:Zhong Fangrui  Han Xiaoyu  Wang Youqing  Lu Yixin
Affiliation:Department of Chemistry & Medicinal Chemistry Program, Life Sciences Institute, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
Abstract:
Keywords:amino acids  asymmetric synthesis  cycloaddition  phosphines  spiro compounds
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