Stereoselective synthesis of C-substituted morpholine derivatives using reductive etherification reaction: total synthesis of chelonin C |
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| Authors: | Gharpure Santosh J Prasad J V K |
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| Affiliation: | Department of Chemistry, Indian Institute of Technology Madras, Chennai-600036, Tamil Nadu, India. sjgharpure@iitm.ac.in |
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| Abstract: | A general strategy is developed for the stereoselective synthesis of C-substituted morpholine derivatives using intramolecular reductive etherification reaction. The method is extended to the first stereoselective total synthesis of (±)-chelonin C. |
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