A turn-on two-photon fluorescent probe for ATP and ADP |
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Authors: | Rao Alla Sreenivasa Kim Dokyoung Nam Hyoseok Jo Hunho Kim Ki Hean Ban Changill Ahn Kyo Han |
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Institution: | Department of Chemistry and the Center for Electro-Photo Behaviors in Advanced Molecular Systems, POSTECH, San 31, Hyoja-dong, Pohang, 790-784, Republic of Korea. |
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Abstract: | An acedan derivative containing Zn(II)-DPA has been developed as a two-photon probe for nucleoside phosphates, which shows enhanced fluorescence toward ATP and ADP at physiological pH 7.4 among other competing anions including AMP; the probe is permeable to cell membranes and thus can be directly used for two-photon imaging of ATP and ADP in live cells. |
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