Kinetic resolution of axially chiral 2,2'-dihydroxy-1,1'-biaryls by palladium-catalyzed alcoholysis |
| |
| Authors: | Aoyama Hiroshi Tokunaga Makoto Kiyosu Junya Iwasawa Tetsuo Obora Yasushi Tsuji Yasushi |
| |
| Institution: | Catalysis Research Center and Division of Chemistry, Graduate School of Science, Hokkaido University, SORST and CREST, Japan Science and Technology Corporation, Sapporo 001-0021, Japan. |
| |
| Abstract: | Palladium-diamine complexes catalyzed kinetic resolution of axially chiral 2,2'-dihydroxy-1,1'-biaryls by alcoholysis of vinyl ethers. The reaction proceeded with high selectivity for various kinds of biaryls. This process is applicable to not only binaphthols but also biphenols, which have been considered to be difficult for the enantioselective synthesis by known catalytic methods. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
