Studies on lysergic acid diethylamide and related compounds—VI: Steric requirements of von braun reaction |
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Authors: | Y Nakahara T Niwaguchi H Ishii |
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Institution: | National Research Institute of Police Science, Chiyoda-ku, Tokyo, Japan;Faculty of Pharmaceutical Sciences, Chiba University, 1-33, Yayoi-cho, Chiba, Japan |
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Abstract: | It has been shown that in the ergot alkaloid series the von Braun reaction is hindered if there is a substituent which is 1,3-diaxial with respect to the nitrogen lone pair in the prefered conformation. |
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