Guang Xing WANG,Jing Xin ZHANG,Shu Feng CHEN,Xiao Tian LIANG* Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050
基金项目:
the National Research Center for Analysis of Drugs and Metabolites for recording NMR and MS data. This project was partially fo
摘 要:
Chrysotricine 1 was isolated from the Chinese herb medicine Hedyotis Chrysotricha and was shown to possess antitumor activity1. Its structure has been elucidated as a novel zwitterionic (-carboline alkaloid containing a 2,2,5-trisubstituted tetrahydrofuranyl group. The (-carboline compounds have attracted considerable attraction in recent years because of their promising and intriguing biological activities2. Recently, we have established the absolute configuration of chrysotricine by the fir…