| Enzymatic Synthesis of Dipeptide Derivatives Containing Non-coded Amino Acids in Organic Solvents |
| |
| 引用本文： | 杨洪,周闯,田桂玲,叶蕴华. Enzymatic Synthesis of Dipeptide Derivatives Containing Non-coded Amino Acids in Organic Solvents[J]. 中国化学, 2002, 20(11): 1354-1357. DOI: 10.1002/cjoc.20020201133 |
| |
| 作者姓名： | 杨洪 周闯 田桂玲 叶蕴华 |
| |
| 作者单位： | YANG，Hong ZHOU，Chuang TIAN，Gui-Ling YE，Yun-HuaKey Laboratory of Bio-organic Chemistry and Molecular Engineering of Education Ministry，College of Chemistry and Molecular Engineering，Peking University，Beijing 100871，China |
| |
| 基金项目： | theNationalNaturalScienceFoundationofChina (No.2 9872 0 0 2 ) |
| |
| 摘 要： | ＩｎｔｒｏｄｕｃｔｉｏｎＥｎｚｙｍａｔｉｃｐｅｐｔｉｄｅｓｙｎｔｈｅｓｉｓｈａｓｄｒａｗｎｍｕｃｈａｔｔｅｎ ｔｉｏｎｂｅｃａｕｓｅｏｆｉｔｓａｄｖａｎｔａｇｅｏｆｅｎｚｙｍｅｓｔｅｒｅｏｓｐｅｃｉｆｉｃｉｔｙ ,ｍｉｌｄｒｅａｃｔｉｏｎｃｏｎｄｉｔｉｏｎｓ ,ｍｉｎｉｍｕｍｓｉｄｅ ｃｈａｉｎｐｒｏｔｅｃｔｉｏｎａｎｄａｖｏｉｄａｎｃｅｏｆｒａｃｅｍｉｚａｔｉｏｎ .Ｂｕｔｔｈｅｓｔｒｉｃｔｓｕｂｓｔｒａｔｅｓｐｅｃｉｆｉｃｉｔｙｏｆｔｈｅｅｎｚｙｍｅｓｌｉｍｉｔｓｔｈｅｉｒａｐｐｌｉｃａｔｉｏｎｓ .…
|
Enzymatic Synthesis of Dipeptide Derivatives Containing Non-coded Amino Acids in Organic Solvents |
| |
| YANG,Hong ZHOU,Chuang TIAN,Gui-Ling YE,Yun-HuaKey Laboratory of Bio-organic Chemistry and Molecular Engineering of Education Ministry,College of Chemistry and Molecular Engineering,Peking University,Beijing ,China. Enzymatic Synthesis of Dipeptide Derivatives Containing Non-coded Amino Acids in Organic Solvents[J]. Chinese Journal of Chemistry, 2002, 20(11): 1354-1357. DOI: 10.1002/cjoc.20020201133 |
| |
| Authors: | YANG Hong ZHOU Chuang TIAN Gui-Ling YE Yun-HuaKey Laboratory of Bio-organic Chemistry Molecular Engineering of Education Ministry College of Chemistry Molecular Engineering Peking University Beijing China |
| |
| Affiliation: | YANG,Hong ZHOU,Chuang TIAN,Gui-Ling YE,Yun-HuaKey Laboratory of Bio-organic Chemistry and Molecular Engineering of Education Ministry,College of Chemistry and Molecular Engineering,Peking University,Beijing 100871,China |
| |
| Abstract: | A series of dipeptide derivatives containing non-coded amino acids, N-Boc-4-X-Phe-Ala-NHNHPh (X=Cl, Br, I, NO 2), were synthesized by using thermoase in organic solvents. The physical data were consistent with the same samples prepared by 3-(diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT). Influence of different substituted groups of the non-coded amino acids and different organic solvents on the enzymatic peptide synthesis was studied. |
| |
| Keywords: | thermoase DEPBT non-coded amino acid enzymatic synthesis peptide |
| 本文献已被 CNKI 等数据库收录！ |
|
