Chemical Conversions of 8,18-Disubstituted Derivatives of 6,16-Diphenyl-1,2,3,11,12,13-hexahydrodibenzo[g,o]-4,14-dioxa-1,5,11,15-tetraazacyclohexadecine-2,12-diones

The chemical properties of 8,18-disubstituted 6,16-diphenyl-1,2,3,11,12,13-tetrahydrodibenzo[g,o]-4,14-dioxa-1,5,11,15-tetraazahexadecine-2,12-diones have been studied, including their interaction with N-nucleophiles (hydroxylamine, hydrazine, semicarbazide, and thiosemicarbazide), acidic and alkaline hydrolysis, and methylation. A hypothesis has been made from analysis of the mass spectral data of the thiosemicarbazide on the preferred existence of 6-substituted 4-phenylquinazoline-2-carbaldehydes in the gas phase as the linear tautomer.