|
|||||
|
|
N-Phosphano nitrogen-containing five-membered aromatic chiral α-sulfoxides as new chiral ligands in asymmetric palladium-catalyzed allylic alkylation: stereoelectronic effects of the substituents on the aromatic rings |
|
| Authors: | Kunio Hiroi Ikuo Izawa Ken-ichi Kawai |
| Institution: | a Department of Synthetic Organic Chemistry, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi 981-8558, Japan b Hoshi University, 2-4-41, Ebara, Shinagawa-ku, Tokyo 142-8501, Japan |
| Abstract: | New chiral ligands, N-diphenylphosphano nitrogen-containing five-membered aromatic compounds bearing chiral sulfinyl groups as the sole chiral source has been developed. The structure of a palladium intermediate derived from the new chiral sulfoxide ligand was determined as a palladium complex with a five-membered chelate ring formed by coordination of the phosphano group and the sulfinyl sulfur atom involved. The stereoelectronic effects of substituents on the aromatic rings are discussed. |
| Keywords: | Asymmetric synthesis Palladium and compounds Alkylation Indoles Pyrroles Sulfoxides |
| 本文献已被 ScienceDirect 等数据库收录！ | |