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Capacitance‐to‐digital: The upgrades of single chip detector
Authors:Tomas Drevinskas  Audrius Maruška  Vitalis Briedis
Affiliation:1. Faculty of Natural Sciences, Department of Biology, Vytautas Magnus University, Kaunas, Lithuania;2. Faculty of Pharmacy, Lithuanian University of Health Sciences, Kaunas, Lithuania
Abstract:The capacitance‐to‐digital single chip detector was upgraded. The paper discusses hardware issues and benefits of the designed/upgraded detector. The device can be operated from rechargeable lithium‐ion battery as stand‐alone, portable system and is capable of transmitting real‐time data wirelessly. The detector and additional modules (battery, battery holder, microcontroller board, wireless module) weight is less than 85 g. Electrophoretic separation in low conductivity 20 mM MES/L‐His buffer, pH 6.1, was performed in order to evaluate detection parameters. The system is capable of quantification of potassium ions down to 0.31 μM. Investigation of differential signal acquisition configuration showed improved performance regarding external noise and temperature fluctuations. The system can be a solution for stand‐alone, field‐portable capillary format separation detector.
Keywords:Capacitance‐to‐digital converter  Capillary electrophoresis  Miniaturization
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