Efficient Synthesis of [1,3]Oxazino[3,2‐f]phenanthridine Derivatives by a Novel 1,4‐Dipolar Cycloaddition Involving a Phenanthridine–Dimethyl Acetylenedicarboxylate Zwitterion and Aromatic Aldehydes |
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| Authors: | Ming Li Lei Pan Li‐Rong Wen |
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| Institution: | Key Laboratory of Eco‐Chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.?R. China, (phone/fax: +86‐532‐84023927) |
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| Abstract: | An efficient synthesis of 1,3]oxazino3,2‐f]phenanthridine derivatives via a three‐component reaction of phenanthridine, dimethyl acetylenedicarboxylate (DMAD), and aromatic aldehydes is described. This novel method is complementary to the classical Huisgen 1,4‐dipolar cycloaddition in that it is well‐suited to the preparation of 1,3]oxazino3,2‐f]phenanthridines. |
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| Keywords: | [1 3]Oxazino[3 2‐f]phenanthridines Multicomponent reactions Dimethyl acetylenedicarboxylate (DMAD) Zwitterions Aldehydes Cycloadditions |
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