First Stereoselective Total Synthesis of Gallicynoic Acids G and H |
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| Authors: | Palakodety Radha Krishna Kadimi Anitha |
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| Affiliation: | 1. D‐211, Discovery Laboratory, Organic Chemistry Division‐III, Indian Institute of Chemical Technology, Hyderabad 500?607, India, (phone: +91‐40‐27193158;2. fax: +91‐40‐27160387) |
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| Abstract: | A stereoselective convergent total synthesis of two acetylenic acids, gallicynoic acid G ( 1 ) and H ( 2 ), is reported, involving asymmetric reduction of alkynones 3 and 4 , respectively, with the Corey? Bakshi? Sibata (CBS) catalyst as a key step (Scheme 3), 3 and 4 being obtained from a common intermediate, the chiral alkynol 12 (Scheme 2). |
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| Keywords: | Stereoselective syntheses Gallicynoic acids G and H |
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