Caragisides A – C,New Isoflavone Glucosides from Caragana conferta with Inhibition of Platelet Aggregation |
| |
| Authors: | Amna Nisar?Khan Itrat Fatima Abdul Malik Huma Rasheed |
| |
| Institution: | 1. International Centre for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi‐75270, Pakistan (phone: +92‐21‐4824926);2. International Centre for Chemical and Biological Sciences, Dr. Panjwani Centre for Molecular Medicine and Drug Research, University of Karachi, Karachi‐75270, Pakistan |
| |
| Abstract: | Caragisides A–C ( 1 – 3 , resp.), three new isoflavone glucosides, were isolated from the BuOH sub‐fraction of the EtOH extract of the whole plant of Caragana conferta, along with ononoside ( 4 ), reported for the first time from this species. The structures of the new compounds were elucidated by spectroscopic techniques including MS and 2D‐NMR spectroscopy. Compounds 1 – 3 showed significant inhibition of platelet aggregation. |
| |
| Keywords: | Caragana conferta Isoflavone glucosides Caragisides A – C Ononoside Glucosides Anti‐platelet‐aggregation activity |
|
|
